SANSORI: Does rigid eye structure help protect astronauts' eyesight?
The SANSORI experiment will investigate the factors involved in vision changes experienced by some astronauts during six-month missions.
Background
Human vision is naturally adapted to the conditions of life on Earth. But when astronauts spend several months in space, both their eyes and eyesight can change and result in blurry or altered vision.
This condition is called Spaceflight-Associated Neuro-Ocular Syndrome (SANS), and it affects 45 to 75 percent of astronauts during six-month space flights. It could be caused by the extra pressure that builds in astronauts' heads when their body fluids shift in a weightless environment.
Scientists are investigating why SANS is so common. For this experiment, Canadian researchers will study whether astronauts who have a particularly rigid eye structure – caused by stiffness in the outer coating of the eye – are less likely to develop SANS. They will also examine whether SANS is more likely to happen when blood vessels in the choroid (a thin layer of tissue in the eye) become engorged.
Objectives
SANSORI aims to:
- examine the causes of vision changes that astronauts may experience during six-month missions
- determine whether higher ocular rigidity (a less flexible eye structure) makes astronauts less likely to develop space-related vision changes
- study whether physical differences in eye structure add to the risk of vision changes in space
Impacts on Earth
Although SANS is a condition that applies specifically to vision changes in astronauts, the knowledge we gain from the SANSORI experiment could help researchers better understand vision problems on Earth.
SANSORI will contribute to what we know about conditions such as glaucoma, idiopathic intracranial hypertension (high blood pressure in the head without known cause) and certain cardiovascular diseases – conditions that, like SANS, are at least partly caused by increased pressure in the head. This research can also help us understand the effects of pressure changes in patients' heads and eyes when they are on prolonged bedrest.
How it works
The SANSORI experiment will test 13 astronauts:
- Researchers will collect data about astronauts' eyesight and the physical properties of their eyes before, during and after their space flights. Researchers will use:
- questionnaires about the astronauts' visual acuity
- various scans, videos and imaging of the eyes to measure astronauts' eye pressure
- ophthalmic MRI reports
- information from exercise sessions
- Researchers will use data sharing to access as much information about the astronauts' vision as possible, and to ensure they have a complete picture of the astronauts' medical history.
Timeline
Data collection for SANSORI began in . The study is scheduled to conclude in late .
Research team
Principal investigator
- Dr. Santiago Costantino, Université de Montréal
Co-investigator
- Dr. Mark Lesk, Université de Montréal, Hôpital Maisonneuve-Rosemont